Now-a-days the applications of nanotechnology and nanomaterial’s can be found in many topical preparations. Topical preparations are used for the localized effects at the site of their application by virtue of drug penetration into the underlying layers of skin or mucous membranes. Topical delivery can be defined as the application of a drug containing formulation to the skin to directly treat cutaneous disorders (e.g. acne) or the cutaneous manifestations of a general disease (e.g. fungal infections) with the intent of containing the pharmacological or other effect of the drug to the surface of the skin or within the skin in this review we discuss structure of skin, skin diseases and different polymeric nanoparticles use for the topical drug delivery.
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